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| The
Yeast Intein Database |
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The Yeast Intein Database is a comprehensive
and curated database devoted to yeast inteins.
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| Inteins
are self-catalytic protein splicing elements. The Yeast Intein Database
and Registry, is a curated compilation of published and unpublished
information about protein splicing. It presents general information
as well as detailed data for each yeast intein, including tabulated
comparisons and a comprehensive bibliography. An intein-specific BLAST
server is now available to assist in identifying new inteins. |
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| Intein
Name |
Ctr VMA
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| Intein
id |
YSTIN011 |
| Intein
Class |
Experimental
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| Prototype
Allele |
Sce VMA
|
| Organism
Name |
Candida tropicalis (nucleus) |
| Exiein
Name |
Vacuolar ATPase (H+-transporting ATP synthase), subunit A |
| Intein
Class |
Experimental |
| Organism
Description |
Yeast |
| Domain
of Life |
Eucarya |
| Endonuclease
Activity |
-- |
| Endonuclease
Motif |
DOD |
| Location
in Extein |
G283 |
| Inert
Site Comment |
VMA-a |
| Intein
Size |
471 |
| Intein
N Terminal |
SNSDVIIYVG/C |
| Intein
C Terminal |
HN/CGERGNEMAE |
| Accession
No |
A46080 in NCBI/protein |
| Intein
aa Sequence |
>gi|1076955|pir||A46080 Ctr VMA intein (including -1 and +1 extein residues)
GCFTKGTQVMMADGADKSIESIEVGDKVMGKDGMPREVVGLPRGYDDMYKVRQLSSTRRNAKSEGLMDFT
VSADHKLILKTKQDVKIATRKIGGNTYTGVTFYVLEKTKTGIELVKAKTKVFGHHIHGQNGAEEKAATFA
AGIDSKEYIDWIIEARDYVQVDEIVKTSTTQMINPVHFESGKLGNWLHEHKQNKSLAPQLGYLLGTWAGI
GNVKSSAFTMNSKDDVKLATRIMNYSSKLGMTCSSTESGELNVAENEEEFFNNLGAEKDEAGDFTFDEFT
DAMDELTINVHGAAASKKNNLLWNALKSLGFRAKSTDIVKSIPQHIAVDDIVVRESLIAGLVDAAGNVET
KSNGSIEAVVRTSFRHVARGLVKIAHSLGIESSINIKDTHIDAAGVRQEFACIVNLTGAPLAGVLSKCAL
ARNQTPVVKFTRDPVLFNFDLIKSAKENYYGITLAEETDHQFLLSNMALVHNC |
| Block
A |
CFTKGTQVMMADG 13 |
| Block
B |
LMDFTVSADHKLIL 78 |
| Block
C |
LLGTWAGIG 210 |
| Block
D |
VKSIPQHI 325 |
| Block
E |
LIAGLVDAAG 345
|
| Block
H |
TSFRHVARGLVKIAHSLGI 379 |
| Block
F |
YGITLA**EETDHQFL 462 |
| Block
G |
NMALVHNC 472
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| Contributed
by |
Gary Dean |
| Comments |
The Ctr VMA extein gene has a typical Candida tropicalis intron and is the first gene reported to have both an intron and an intein (Gu 1993).
Ctr VMA is a nuclear gene |
| References |
Gu 1993
Steuer 2004 |
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