The Yeast Intein Database

The Yeast Intein Database is a comprehensive and curated database devoted to yeast inteins.


Inteins are self-catalytic protein splicing elements. The Yeast Intein Database and Registry, is a curated compilation of published and unpublished information about protein splicing. It presents general information as well as detailed data for each yeast intein, including tabulated comparisons and a comprehensive bibliography. An intein-specific BLAST server is now available to assist in identifying new inteins.

 

Intein Name Cla PRP8
Intein id YSTIN003
Intein Class Theoretical
Prototype Allele Cne-AD PRP8
Organism Name Cryptococcus laurentii strain CBS139
Exiein Name PRP8, pre-mRNA splicing factor
Intein Class Theoretical
Organism Description Fungi, Basidiomycete yeast, taxon:5418
Domain of Life Eucarya
Endonuclease Activity --
Endonuclease Motif DOD
Location in Extein S59?
Inert Site Comment PRP8-a,same as A1578 in Sce PRP8
Intein Size 522
Intein N Terminal TWEGLFWEKS/C
Intein C Terminal HN/SGFEESMKFK
Accession No AAX38551 in NCBI/protein
Intein aa Sequence >gi|61105788|gb|AAX38551.1|[61105788] Cla PRP8 intein (including -1 and +1 extein residues) SCHAEGTELIKFDRSVVKVEDVVEGDRLLGPDGSPRLVSNLVSGCDRLYRFEFSRSGGEVESLVVTDNHIMMLKRANVVL SGSGDAGQLEVLDQISVREQFEIVQKTAAEVAAMSEAEREQYRVYRSEGFEHYEQPVDVHPYFLGLWLGDDSRSANAATN GEPEVRKFLTDYAGELDMHLAHHGDEKRDRRTVKAARLAAGWTLLPRTEGKAGAWIPPATAGYVAPTHSPAPNLRDADGH RSVSAPSQVDEKPEVSHDDEDMEISDTEEEQSDAIEEIEADDDDAAIVMEGPHGQLTPGGRRDEMQPAKARRRVRRLNRN QRYGDLADAEVEALLEDVVSGGQSDGQVVRSAQLLDKLQSLGVATSNEKEKPAQGSKHIPQVYLENTRDVRLRVLAGLLD SHGCLVSPENCYMFSQPETDGRLFWDAVHLARSLGFGVSTDRKTQMNPGSDVATPHLLALITGDLTQVPCLLRRQQAVQR YLPQQHTFRIKSVTLESKSTPWYGFAVDSDRQYLRHDWMVLHNS
Block A CHAEGTELIKFDR 13
Block B VESLVVTDNHIMML 72
Block C FLGLWLGDD 150
Block D SKHIPQVY 382
Block E VLAGLLDSHG 402
Block H ETDGRLFWDAVHLARSLGF 435
Block F STPWYGFAVDSDRQYL 513
Block G DWMVLHNS 523
Contributed by Margi Butler
Comments Most other PRP8 inteins are mini-inteins
References Butler 2005

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