REB, or Restriction Enzy Base is a comprehensive database which gives the complete information about restriction enzymes, methyltranferases and related proteins involved in the process of restriction modification.Restriction enzymes have come up with a wide range of applications in the recent past including Southern hybridization analysis, DNA sequencing and global gene expression analysis etc. Their importance to biotechnology is apparent when looking through the catalogue of any company that supplies reagents for molecular biological work.

Keeping this in mind REB has been developed as a user friendly database which gives a wide range of details about restriction enzymes which include the recognition sequence, type, subtype, growth temperature, organism, isoschizomers and type of cuts produced.
In addition to this REB also includes information about related proteins like nicking enzymes, orphan methyltrannsferases, homing enzymes, specificity subunits, control proteins and methyl-directed restriction enzymes.

There are currently more than 4000 biochemically- characterized enzymes in REB which include around 600 enzymes which are commercially available and also the company which supplies them. Apart from this REB also provides the user with a very efficient multitask tool which finds the recognition sequences and the corresponding restriction enzymes for any DNA sequence given as input.

Thus REB has turned out to be a very potential database for commercial purpose as well as for molecular biology research.

The REB is supported by IBI Biosolutions Pvt. Ltd., a company certified by American Quality Standards Registrar and recognized by NABCB that aims to become a complete Innovation Driven and Knowledge Process Outsourcing company in the Life Sciences Arena.