| p53 Database | ||||||||||||||
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p53 Structures |
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Protein Interaction of p53:
| Name of Interactor | Type |
| ABL | Direct |
| ADP ribosyl transferase | Direct |
| ADP ribosylation factor like 3 | Direct |
| Actin alpha, skeletal muscle 1 | Direct |
| Apex nuclease | Direct |
| Ariadne 2 | Direct |
| BRCA1 | Direct |
| BTB (POZ) domain containing 2 | Direct |
| Bcl 2 | Direct |
| CDC2 | Direct |
| CDC25C | Direct |
| Chemokine CC motif ligand 18 | Direct |
| Complement receptor 2 | Direct |
| Cyclin A2 | Direct |
| Cyclin dependent kinase inhibitor 2C | Direct |
| Cytochrome c oxidase assembly protein COX17 | Direct |
| DNA topoisomerase I | Direct |
| DNA topoisomerase II alpha | Direct |
| Deleted in lymphocytic leukemia 1 | Direct |
| Dishevelled 2 | Direct |
| E2F transcription factor 1 | Direct |
| ERCC3 | Direct |
| ERCC6 | Direct |
| ERH | Direct |
| Early growth response protein 1 | Direct |
| Estrogen receptor alpha | Direct |
| Estrogen sulfotransferase | Direct |
| Eukaryotic translation elongation factor 2 | Direct |
| FXYD domain containing ion transport regulator 6 | Direct |
| Glucocorticoid receptor | Direct |
| HSP90A | Direct |
| HSU79303 | Direct |
| Heat shock 70 KD protein 1A | Direct |
| Heat shock protein 27 | Direct |
| High mobility group box 1 | Direct |
| High mobility group box 2 | Direct |
| Huntingtin | Direct |
| Hypothetical protein MGC2494 | Direct |
| I kappa B alpha | Direct |
| Interferon gamma inducible protein 16 | Direct |
| Ku antigen, 70kDa | Direct |
| LAMA4 | Direct |
| M phase phosphoprotein 6 | Direct |
| MAD2L1 binding protein | Direct |
| MDM2 | Direct |
| MGC33889 | Direct |
| Nucleolin | Direct |
| Nucleophosmin 1 | Direct |
| PML | Direct |
| Platelet activating factor acetylhydrolase isoform 1B gamma subunit | Direct |
| Prohibitin | Direct |
| Protease inhibitor 9 | Direct |
| Proteasome 26S subunit, non-ATPase, 11 | Direct |
| Protein phosphatase 1, catalytic subunit, alpha isoform | Direct |
| Protocadherin alpha 4 | Direct |
| RAD51 | Direct |
| Replication factor A protein 1 | Direct |
| Ribonucleotide reductase M2 subunit | Direct |
| S100 calcium binding protein A4 | Direct |
| S100 calcium binding protein, beta | Direct |
| SMA3 | Direct |
| SMAD, mothers against DPP homolog 2 (Drosophila) | Direct |
| SMAD3 | Direct |
| Secretory carrier membrane protein 1 | Direct |
| Somatostatin receptor 3 | Direct |
| Spermidine/spermine N(1) acetyltransferase | Direct |
| Syntaxin 5A | Direct |
| TCP 1 epsilon | Direct |
| TFDP1 | Direct |
| TFIIH 62 kDa subunit | Direct |
| THAP8 | Direct |
| Topoisomerase DNA II, beta | Direct |
| Transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) | Direct |
| Transcription factor Sp1 | Direct |
| Transcription factor Sp3 | Direct |
| Tumor necrosis factor ligand superfamily member 5 | Direct |
| Ubiquitin B | Direct |
| WD repeat domain 33 | Direct |
| YB-1 | Direct |
| ZNF191 | Direct |
| Zinc finger, CCHC domain containing 10 | Direct |
| eIF2beta | Direct |
| TAF9 RNA polymerase II | Direct |
| Core promoter element binding protein | Direct |
| Thyroid hormone receptor interactor 15 | Direct |
| RecQ protein like 3 | Direct |
| RecQ protein like 2 | Direct |
| Fibulin 4 | Direct |
| Ribonucleotide reductase M2 B | Direct |
| TF3B90 | Direct |
| TATA box binding protein (TBP) associated factor RNA polymerase I A 48kDa | Direct |
| TAF1B | Direct |
| TAF1C | Direct |
| STE20 like kinase MST1 | Direct |
| Glycogen synthase kinase 3 beta | Direct |
| WW domain containing oxidoreductase | Direct |
| Tumor protein p53 binding protein 1 | Direct |
| 14-3-3 gamma | Direct |
| Homeodomain interacting protein kinase 2 | Direct |
| Wilms tumor 1 | Direct |
| Scotin | Direct |
| UbcH7 associated protein 1 | Direct |
| ATM | Direct |
| HIPK1 | Direct |
| Guanine nucleotide binding protein-like 3 (nucleolar) | Direct |
| TAF9L | Direct |
| HSP90B | Direct |
| PCAF | Direct |
| COP9, subunit 5 | Direct |
| PIASY | Direct |
| COP9,subunit 3 | Direct |
| Thyroid hormone receptor, beta | Direct |
| Zinc finger protein 363 | Direct |
| FRP1 | Direct |
| Sirtuin 1 | Direct |
| DNA primase small subunit | Direct |
| Ubiquitin conjugating enzyme E2I | Direct |
| Cyclin H | Direct |
| Chromodomain helicase DNA binding protein 3 | Direct |
| RelA-associated inhibitor | Direct |
| P53DINP1 | Direct |
| SIN3A | Direct |
| Inhibitor of growth 4 | Direct |
| CCAAT binding factor | Direct |
| COP9 signalosome subunit 4 | Direct |
| AT rich interactive domain 3A | Direct |
| Zinc fingers and homeoboxes 1 | Direct |
| Topoisomerase I binding arginine serine rich | Direct |
| Tumor suppressor p53 binding protein 2 | Direct |
| G protein pathway suppressor 2 | Direct |
| TP53 regulating kinase | Direct |
| Ankyrin repeat domain 2 | Direct |
| Cdk5 and Abl enzyme substrate 2 | Direct |
| G protein pathway suppressor 1 | Direct |
| Pleiomorphic adenoma gene like 1 | Direct |
| Protein inhibitor of activated STAT, 1 | Direct |
| SET domain containing protein 7 | Direct |
| Mediator of DNA damage checkpoint 1 | Direct |
| Inhibitor of growth family, member 5 | Direct |
| Cdk5 and Abl enzyme substrate 1 | Direct |
| BTG3 associated nuclear protein | Direct |
| COP9 constitutive photomorphogenic homolog subunit 6 | Direct |
| COP9 constitutive photomorphogenic homolog subunit 7A | Direct |
| COP9 constitutive photomorphogenic homolog subunit 8 | Direct |
| p53 | Direct |
| DNA Polymerase, alpha | Direct |
| Ubiquitin conjugating enzyme E2A | Direct |
| BCLX | Direct |
| TATA box binding protein | Direct |
| CREBBP | Direct |
| BRCA2 | Direct |
| Cycloxygenase 2 | Direct |
| Hepatocyte nuclear factor 4 alpha | Direct |
| RNA polymerase II elongation factor ELL | Direct |
| Survival of motor neuron 1, telomeric | Direct |
| Casein kinase 1, alpha 1 | Direct |
| Mortalin 2 | Direct |
| IKK alpha | Direct |
| Karyopherin alpha 2 | Direct |
| Casein kinase 1, delta | Direct |
| DNA dependent protein kinase catalytic subunit | Direct |
| Pin1 | Direct |
| Mitogen-activated protein kinase 8 | Direct |
| 14-3-3 zeta | Direct |
| Tumor susceptibility gene 101 | Direct |
| Inhibitor of growth 1 | Direct |
| Cyclin G1 | Direct |
| SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | Direct |
| Ubiquitin protein ligase E3A | Direct |
| Telomerase protein component 1 | Direct |
| Protein tyrosine phosphatase PTEN | Direct |
| ERK1 | Direct |
| Zinc finger protein 148 | Direct |
| p73 | Direct |
| Necdin | Direct |
| Vaccinia related kinase 1 | Direct |
| LKB1 | Direct |
| Kruppel-like factor 4 | Direct |
| Ubiquitin specific protease 7 | Direct |
| MAT1 | Direct |
| Serine/threonine protein kinase 6 | Direct |
| MDM4 | Direct |
| Karyopherin beta 1 | Direct |
| Ubiquitin conjugating enzyme E2-25K | Direct |
| Mitogen-activated protein kinase 9 | Direct |
| Mitogen-activated protein kinase 10 | Direct |
| Cytokine inducible kinase | Direct |
| ADA3 | Direct |
| Protein arginine N-methyltransferase 1 | Direct |
| E4F transcription factor 1 | Direct |
| Cell cycle checkpoint kinase | Direct |
| Activating transcription factor 3 | Direct |
| Daxx | Direct |
| SMARCA4 | Direct |
| Tumor protein p63 | Direct |
| Hypoxia inducible factor 1 alpha subunit | Direct |
| PKR protein activator | Direct |
| Dual specificity protein phosphatase CDC14A | Direct |
| Cell division cycle 14 homolog B | Direct |
| Metastasis associated protein MTA1 | Direct |
| TRAP 80 | Direct |
| Pituitary tumor-transforming protein 1 | Direct |
| TRAP220 | Direct |
| Glutathione S-transferase M4 | Direct |
| CDC42 | Direct |
| S100 calcium binding protein A2 | Direct |
| ERK2 | Direct |
| Protein kinase C alpha | Direct |
| Protein kinase R | Direct |
| Annexin III | Direct |
| Homeo box 7 | Direct |
| Calpain, large polypeptide L1 | Direct |
| Cyclin dependent kinase 5 | Direct |
| Cyclin dependent kinase 2 | Direct |
| Casein kinase II, beta | Direct |
| Casein kinase II, alpha 1 | Direct |
| Small nuclear ribonucleoprotein polypeptide N | Direct |
| BRCA1 associated ring domain 1 | Direct |
| Metastasis associated protein MTA2 | Direct |
| Thymidine kinase soluble | Direct |
| AP2 gamma | Direct |
| DDX5 | Direct |
| 24 dehydrocholesterol reductase | Direct |
| Nucleoside phosphorylase | Direct |
| COP1 | Direct |
| Inorganic pyrophosphatase | Direct |
| Protein phosphatase 2A, catalytic subunit, alpha isoform | Direct |
| BCR | Direct |
| Myeloid cell nuclear differentiation antigen | Direct |
| NAD(P)H dehydrogenase, quinone 1 | Direct |
| Hyaluronan binding protein 4 | Direct |
| Cyclin dependent kinase 9 | Direct |
| E1A binding protein p300 | Direct |
| NEDD8 | Direct |
| S100 Calcium binding protein A8 | Direct |
| FAK | Direct |
| TP53 regulated inhibitor of apoptosis 1 | Direct |
| Ras associated protein Rab4 | Direct |
| MDM2
Retinoblastoma 1 |
Complex |
| BCL2
binding component 3 BCLX |
Complex |
| Homeodomain
interacting protein kinase 2 Skeletal muscle LIM protein 3 |
Complex |
| Glucocorticoid
receptor Oncoprotein Mdm2 |
Complex |
| Transcription
factor 2A, 2 Transcription factor 2A, 1 |
Complex |
| MAT1
Cyclin dependent kinase 7 |
Complex |
| Thyroid
hormone receptor interactor 15 COP9, subunit 5 COP9,subunit 3 COP9 signalosome subunit 4 G protein pathway suppressor 1 COP9 constitutive photomorphogenic homolog subunit 6 COP9 constitutive photomorphogenic homolog subunit 7A COP9 constitutive photomorphogenic homolog subunit 8 |
Complex |
| Oncoprotein
Mdm2 Ribosomal protein L5 |
Complex |
| MSH2
RecQ protein like 3 RAD51 |
Complex |