| p53 Database |
|
|
|
p53 Structures |
|
|
|
Mammals |
|
|
|
|
|
|
|
|
| |
|
© 2007 IBI Biosolutions Pvt. Ltd. |
|
|
HUMAN p53
Due to the large number of monoclonal antibodies which recognized human p53, the table has been seperated in three parts :
Human p53 - amino-terminus
Name |
Epitope Location |
Antigen used for immunization |
Isotype |
Other species recognition |
WB |
IP |
Reference |
Comercial availability |
Bp53-1 |
6-15 |
Human p53 |
IgG1 |
? |
Yes |
Yes |
10, 18 |
? |
Bp53-31 |
6-15 |
Human p53 |
IgG3 |
? |
Yes |
Yes |
10, 18 |
? |
Bp53-8 |
6-15 |
Human p53 |
IgG1 |
? |
Yes |
Yes |
10, 18 |
? |
Bp53-22 |
6-20 |
Human p53 |
IgG1 |
? |
Yes |
Yes |
10, 18 |
? |
Bp53-25 |
6-20 |
Human p53 |
IgG1 |
? |
Yes |
Yes |
10, 18 |
? |
Bp53-27 |
6-20 |
Human p53 |
IgG1 |
? |
Yes |
Yes |
10, 18 |
? |
DO2 |
10-16 |
Human p53 |
IgG |
? |
Yes |
Yes |
9, 15 |
Yes |
L134 |
11-20 |
Human p53 |
IgG1 |
No |
Yes |
Yes |
11, 12 |
No |
B17 |
16-25 |
Human p53 |
IgG2a |
Yes |
Yes |
Yes |
11, 12 |
No |
X77 |
16-25 |
Xenopus p53 |
IgG1 |
Yes |
Yes |
Yes |
19 |
No |
X73 |
16-25 |
Xenopus p53 |
IgG1 |
Yes |
Yes |
Yes |
19 |
No |
X18 |
16-25 |
Xenopus p53 |
IgG1 |
Yes |
Yes |
Yes |
19 |
No |
Bp53-2 |
16-25 |
Human p53 |
IgG1 |
? |
Yes |
Yes |
10, 18 |
No |
Bp53-2 |
16-25 |
Human p53 |
IgG1 |
? |
Yes |
Yes |
10, 18 |
No |
Bp53-13 |
16-25 |
Human p53 |
IgG2a |
? |
Yes |
Yes |
10, 18 |
No |
Bp53-24 |
16-25 |
Human p53 |
IgG2b |
? |
Yes |
Yes |
10, 18 |
No |
Bp53-28 |
16-25 |
Human p53 |
IgG2a |
? |
Yes |
Yes |
10, 18 |
No |
C36 |
16-30 |
Human p53 |
IgG1 |
Yes |
Yes |
Yes |
11, 12 |
No |
H461 |
16-30 |
Human p53 |
IgG1 |
Yes |
Yes |
Yes |
11, 12 |
No |
X87 |
16-30 |
Xenopus p53 |
IgG1 |
Yes |
Yes |
Yes |
18 |
No |
X44 |
16-30 |
Xenopus p53 |
IgG1 |
Yes |
Yes |
Yes |
18 |
No |
X61 |
16-30 |
Xenopus p53 |
IgG1 |
Yes |
Yes |
Yes |
18 |
No |
X91 |
16-30 |
Xenopus p53 |
IgG1 |
Yes |
Yes |
Yes |
18 |
No |
Bp53-14 |
16-30 |
Human p53 |
IgG2a |
? |
Yes |
Yes |
10, 18 |
No |
DO7 |
21-25 |
Human p53 |
IgG2b |
? |
Yes |
Yes |
9, 15 |
Yes |
DO1 |
21-25 |
Human p53 |
IgG2a |
? |
Yes |
Yes |
9, 15 |
Yes |
Bp53-4 |
21-25 |
Human p53 |
IgG1 |
? |
Yes |
Yes |
10, 18 |
No |
BP53-12 |
20-25 |
Human p53 |
IgG2a |
? |
Yes |
Yes |
10, 18 |
Yes |
BP53-11 |
20-25 |
Human p53 |
IgG2a |
? |
Yes |
Yes |
10, 18 |
No |
BP53-19 |
20-23 |
Human p53 |
IgG |
Yes |
Yes |
Yes |
10, 18 |
No |
DO13 |
26-35 |
Human p53 |
IgG1 |
? |
Yes |
Yes |
9, 16 |
No |
PAb1801 |
46-55 |
Human p53 |
IgG1 |
No |
Yes |
Yes |
3, 5, 12 |
Yes |
H447 |
46-55 |
Human p53 |
IgG1 |
No |
Yes |
Yes |
11, 12 |
No |
H279 |
46-55 |
Human p53 |
IgG1 |
No |
Yes |
Yes |
11, 12 |
No |
DO14 |
56-65 |
Human p53 |
IgG1 |
? |
Yes |
Yes |
16 |
No |
Bp53-20 |
56-65 |
Human p53 |
IgG1 |
? |
Yes |
Yes |
10, 18 |
No |
Only mAbs that have been experimentally tested either by ELISA, immunoprecipitation or western blot are listed on these tables.
From the epitope sequence, it is quite possible that other mAbs react with this species.
Human p53 - central region
Name |
Epitope
Location |
Antigen use for immunization |
Isotype |
Other species recognition |
WB |
IP |
Reference |
Comercial availability |
HO15.4 |
86-95 |
Human p53 |
IgG2a |
No |
Yes |
Yes |
13 |
No |
HO16.4 |
86-95 |
Human p53 |
IgG2a |
No |
Yes |
Yes |
13 |
No |
HP64 |
171-185 |
Human p53 |
IgG1 |
Yes |
Yes |
Yes |
11,12 |
No |
HO3.5 |
181-190 |
Human p53 |
IgG1 |
No |
Yes |
Yes |
13 |
No |
HO31.1 |
181-190 |
Human p53 |
IgG1 |
No |
Yes |
Yes |
13 |
No |
DO11 |
181-190 |
Human p53 |
IgG1 |
? |
Yes |
Yes |
16 |
No |
HO13.1 |
211-220 |
Human p53 |
IgG2b |
Yes |
Yes |
Yes |
12 |
No |
PAb240 |
213-217 |
Murine p53 |
IgG1 |
Yes |
Yes |
Yes |
6,7,8 |
Yes |
DO12 |
256-270 |
Human p53 |
IgG1 |
? |
Yes |
Yes |
16 |
No |
Only mAbs that have been experimentally tested either by ELISA, immunoprecipitation or western blot are listed on these tables.
From the epitope sequence, it is quite possible that other mAbs react with this species.
Human p53 - carboxy-terminus
Name |
Epitope Location |
Antigen used for immunization |
Isotype |
Other species recognition |
WB |
IP |
Reference |
Comercial availability |
HO7.1 |
291-300 |
Human p53 |
IgG2a |
No |
Yes |
Yes |
13 |
No |
HO33.8 |
291-300 |
Human p53 |
IgG2a |
No |
Yes |
Yes |
13 |
No |
HO8.1 |
306-361 |
Human p53 |
IgG1 |
Yes |
Yes |
Yes |
13 |
Yes |
PAb122 |
371-380 |
Mouse p53 |
IgG2b |
Yes |
Yes |
Yes |
1, 4, 15 |
Yes |
PAb421 |
371-380 |
Mouse p53 |
IgG2a |
Yes |
Yes |
Yes |
2, 4, 15 |
Yes |
HR231 |
371-380 |
Human p53 |
IgG2b |
Yes |
Yes |
Yes |
10, 11 |
No |
Bp53-3 |
371-380 |
Human p53 |
IgG2a |
? |
Yes |
Yes |
10, 18 |
No |
Bp53-30 |
371-380 |
Human p53 |
IgG2b |
? |
Yes |
Yes |
10, 18 |
No |
Bp53-6 |
376-380 |
Human p53 |
IgG1 |
? |
Yes |
Yes |
10, 18 |
No |
ICA9 |
388-393 |
synthetic peptide |
IgG |
? |
? |
Yes |
14 |
No |
Only mAbs that have been experimentally tested either by ELISA, immunoprecipitation or western blot are listed on these tables.
From the epitope sequence, it is quite possible that other mAbs react with this species
|