Knowledge of complete virus genome sequences helps biologists to develop a fundamental understanding of viral replication and host pathogen interactions. However, the consistence analysis of viral proteins in the absence of many of today's bioinformatics approaches has resulted in the level of organization and annotation of viral genome sequence consistence to grow. Additional complete protein sequences can be retrieve a single FASTA format files for easy import into other sequence analysis program. The protein families are a rich source of information for functional and evolutionary studies and the alignment of conserved sequences regions facilitate the direct study of construction of sequence profile.

The Leukemia Virus Database (LeuBase), a knowledge-base of leukemia virus genes and proteins that contains detailed information of the genes and predicted protein sequences from 7 completely sequenced genomes (Abelson murine leukemia virus; Bovine leukemia virus; Feline leukemia virus; Friend leukemia virus; Gibbon ape leukemia virus; Molony murine leukemia virus; Rauscher murine leukemia virus). Out of 7 genomes of leukemia virus, the one genome (Bovine leukemia virus) has shown the maximum length i.e. about 81419 nt long and one virus (Feline leukemia virus) has shown approximately 53 CDs in the genome, it was predicted on the basis of Open Reading Frame (ORF's). The database contains the information of DNA sequence, protein sequence, length of DNA & protein sequence and G+C%. For each family (gag, pol, env), an alignment of the conserved regions, functional and taxonomy information, and links to DNA & Protein sequences is retrieved through this database.

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