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Words
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Description
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| Homology
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Two or more biological species, systems or molecules that share a common evolutionary ancestor. (general) Two or more gene or protein sequences that share a significant degree of similarity, typically measured by the amount of identity (in the case of DNA), or conservative replacements (in the case of protein), that they register along their lengths. Sequence "homology" searches are typically performed with a query DNA or protein sequence to identify known genes or gene products that share significant similarity and hence might inform on the ancestry, heritage and possible function of the query gene. |
| Homolog
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One of a pair of chromosomes, in which one is obtained from the organism's maternal parent and the other from the paternal parent; found in diploid cells. |
| Homologous genes
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Genes that share a common evolutionary ancestor. |
| Homologous protein
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A protein that is related to another by common evolutionary history. |
| Homology domain
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A region in a protein sequence with similarity to an otherwise unrelated protein. This term should be used only if the region is of a size sufficient to form a domain |
| High-scoring segment pair (HSP)
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Local alignments with no gaps that achieve one of the highest alignment scores in a given search. |
| Hypothesis
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An idea that can be experimentally tested; an idea with the lowest level of confidence. |
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