|
Words
|
Description
|
| cDNA
|
A DNA molecule usually obtained by a reverse transcription of an mRNA molecule. |
| cds
|
Coding sequence. |
| Cell
|
The basic unit of any living organism. |
| Cell Cycle
|
The life cycle of a cell which is marked by cell division which is separated into four phases: G1, S, G2, and M. DNA replication is confined to the S(synthesis) phase, and chromosomal separation in the M (mitotic) phase. |
| Conserved sequence
|
A conserved sequence is a DNA or protein sequence with a high degree of sequence identity to other sequences in that species, or in others. |
| Consensus sequence
|
A single sequence delineated from an alignment of multiple constituent sequences that represents a "best fit" for all those sequences. A "voting" or other selection procedure is used to determine which residue (nucleotide or amino acid) is placed at a given position in the event that not all of the constituent sequences have the identical residue at that position. |
| Central dogma
|
The path of information flow in DNA organisms (DNA -> RNA -> proteins). |
| Codon
|
A sequence of three nucleotides in messenger RNA that codes for a single amino acid |
| Contig
|
A length of contiguous sequence assembled from partial, overlapping sequences, generated from a "shotgun" sequencing project. Contigs are typically created computationally, by comparing the overlapping ends of several sequencing reads generated by restriction enzyme digestion of a segment of genomic DNA. The creation of contigs in the presence of sequencing errors, ambiguities and the presence of repeats is one of the most computationally challenging aspects of the role of Bioinformatics in genome analysis. |
| Complementary sequence
|
A sequence of bases that can form a double-stranded structure by matching base pairs. |
| Convergence
|
The end-point of any algorithm that uses iteration or recursion to guide a series of data processing steps. An algorithm is usually said to have reached convergence when the difference between the computed and observed steps falls below a pre-defined threshold. |
| Complementary sequence
|
A sequence of bases that can form a double-stranded structure by matching base pairs. |
