Bioinformatics Research Laboratory, IBI Biosolutions Pvt. Ltd. India

What is DB-DRD4?

The Dopamine D4 receptor Database (DB-DRD4) is a publicly accessible, relational database, provides comprehensive data related to the DRD4 gene encoded proteins involved in various behavioral phenotypes, including autonomic nervous systemdysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking function and is a candidate gene for several behavioral disorders like parkinson's disease and schizophrenia. This database consolidates  sequence information  from SwissProt (release 54.6), and GenBank (flat file release 162.0), in which sequences are classified according to a hierarchy of different classes, families and sub-families, based on extensive literature search and contains 254 publically available sequences from 51 genera.

The Database DB-DRD4 include following details regarding to Dopamine D4 Receptor Sequences:

1.	GenBank Accession No., SwissProt & GenBank Entry and Organism Name of the DRD4 sequences of 69 species and synthetic construct.
2.	Organism classification.
3.	Signature (one letter code) of the G-protein coupled receptor family I (PS50262) with their C-terminal and N-terminal position.
4.	Amino acid residues (one letter code) of predicted transmembrane regions with their C-terminal and N-terminal position.
5.	Amino acid length of Dopamine receptor D4 sequences.
6.	Amino acid sequence of Dopamine receptor D4 sequences.