| 1. |
From
where the data have been collected ? |
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We
collected DRD4 data from three sources: a) Manual extracts from
relevant papers. b) Genbank sequences. c) Swiss Prot entries. |
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| 2. |
What
are the content of database DRD4 ? |
|
The
Database DRD4 basically contain all information related to the dopamine
and DRD4. |
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| 3. |
What
is Dopamine ? |
|
Dopamine
is a hormone and neurotransmitter in the brain released by the hypothalamus
occurring in a wide variety of animals, including both vertebrates
and invertebrates. Chemically, it is a phenethylamine. and is produced
in several areas of the brain, including the substantia nigra. |
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| 4. |
What
are the function of Dopamine ? |
|
Dopamine
has many functions in the brain, including important roles in behavior
and cognition, motor activity, motivation and reward, regulation
of milk production, sleep, mood, attention, and learning. |
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| 5. |
What
is DRD4 ? |
|
It
is basically the one of the receptor of Dopamine. The DRD4 have
many variants. These variants differ in a variable number tandem
repeat domain present within the coding sequence of exon 3. Some
of these alleles are associated with greater incidence of certain
diseases. |
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| 6. |
Why
there is need for the Database DRD4 ? |
| |
As
the DRD4 is associated with many diseases such as personality disorder,
AHDH, bipolar disorder, depression, etc. By this database you can
retrive the detailed information related to the DRD4 receptor and
its sequences, which would help in dealing a lots of diseases related
to it. |